About isoflurane
Volatile inhaled general anesthetic
Used for
- Maintaining general anesthesia during surgery.
Usual adult dose
Inhaled concentration is adjusted by an anesthesia professional; typically 1–2.5% for maintenance.
Usual dose in children
Inhaled concentration is individually adjusted by an anesthesia professional; often 1.5–2.5% for maintenance.
Common side effects
- Low blood pressure
- Slow or irregular heartbeat
- Breathing suppression
- Nausea and vomiting
Important warnings
- For administration only by trained anesthesia professionals with airway and monitoring equipment.
- Can trigger malignant hyperthermia, a rare, life-threatening reaction.
- May prolong the QT interval and cause abnormal heart rhythms.
- Can cause liver injury, rarely severe.
Pregnancy
Use only when clinically necessary; fetal effects and risks depend on the procedure and exposure.
Breastfeeding
No specific data establish safety; anesthetic exposure is brief, but clinical guidance should determine when breastfeeding resumes.
Interactions
- Other anesthetics, opioids, and sedatives can increase breathing and blood pressure effects.
- Epinephrine and other sympathomimetics may increase the risk of abnormal heart rhythms.
- Nondepolarizing muscle relaxants may have stronger effects.
- Isoniazid may increase the risk of liver injury.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.