About vigabatrin
Antiepileptic medicine
Used for
- Seizures that have not responded to other treatments
- Infantile spasms
Usual adult dose
For difficult-to-control focal seizures: usually 1,000–3,000 mg daily in two doses. Doses are individualized.
Usual dose in children
For infantile spasms: usually 50 mg/kg daily, increased if needed to 150 mg/kg daily in two doses.
Common side effects
- Sleepiness, dizziness, and fatigue
- Weight gain
- Blurred or double vision
- Permanent loss of peripheral vision
Important warnings
- Can cause permanent vision loss; eye monitoring is required before and during treatment.
- May cause suicidal thoughts, mood changes, or worsening seizures.
- Stopping suddenly may trigger seizures; doses should be reduced gradually.
- Can cause severe sleepiness and impair coordination.
Pregnancy
May harm an unborn baby. Use during pregnancy only when benefits outweigh risks; discuss pregnancy plans with a clinician.
Breastfeeding
Information is limited; vigabatrin may enter breast milk. Discuss risks and benefits with a clinician.
Interactions
- Phenytoin levels may decrease.
- Can reduce the amount of clonazepam needed.
- May worsen sedation with alcohol or other medicines that cause sleepiness.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.