About chlorpromazine hydrochloride
First-generation antipsychotic (phenothiazine)
Used for
- Schizophrenia and other psychotic disorders
- Severe nausea and vomiting
- Agitation or severe behavioral disturbance
Usual adult dose
By injection, doses vary by indication; commonly 25–50 mg, repeated cautiously if needed.
Usual dose in children
Specialist-directed dosing based on age and weight; injection use is generally restricted to specific situations.
Common side effects
- Sleepiness, dizziness, and low blood pressure
- Dry mouth, blurred vision, and constipation
- Movement disorders, including tremor or muscle stiffness
- Injection-site pain or irritation
Important warnings
- May cause severe low blood pressure, especially with injection.
- Can prolong the QT interval and rarely cause dangerous heart rhythms.
- Seek urgent care for fever, severe stiffness, or confusion.
- Use caution with older adults, heart disease, or seizure disorders.
Pregnancy
Use only when clinically necessary; treatment near delivery may affect the newborn.
Breastfeeding
May cause infant drowsiness or other effects; clinical guidance is needed.
Interactions
- Alcohol, opioids, and sedatives increase drowsiness and breathing risks.
- Medicines that prolong QT increase abnormal heart-rhythm risk.
- Blood-pressure medicines can increase low blood pressure.
- Anticholinergic medicines can worsen constipation, blurred vision, or urinary retention.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.