About glyburide
Sulfonylurea diabetes medicine
Used for
- Treats type 2 diabetes alongside diet and activity measures.
Usual adult dose
Usually 2.5–5 mg once daily with breakfast; adjusted gradually according to blood glucose.
Common side effects
- Low blood sugar, sometimes severe
- Nausea or stomach upset
- Weight gain
- Skin rash or sun sensitivity
Important warnings
- Can cause prolonged or severe low blood sugar, especially with missed meals.
- Not suitable for type 1 diabetes or diabetic ketoacidosis.
- Use cautiously with kidney or liver problems; monitoring may be needed.
- Avoid excess alcohol, which can affect blood sugar and cause reactions.
Pregnancy
Generally avoided during pregnancy; insulin is usually preferred. Medical supervision is needed when changing treatment.
Breastfeeding
May be unsuitable because of possible infant exposure and low blood sugar; seek clinician guidance.
Interactions
- Other diabetes medicines and insulin can increase low blood sugar.
- Some antibiotics, antifungals, and anti-inflammatory medicines may increase its effects.
- Steroids and some diuretics may raise blood sugar and reduce glucose control.
- Alcohol can cause reactions and make blood sugar less predictable.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.