About itraconazole
Triazole antifungal
Used for
- Fungal infections of the skin, nails, mouth, or lungs
- Certain serious fungal infections, including histoplasmosis and aspergillosis
Usual adult dose
Varies by infection: commonly 100–200 mg once or twice daily; treatment length ranges from days to months.
Usual dose in children
Specialist-directed; dosing depends on the infection and the child’s weight.
Common side effects
- Nausea, stomach pain, or diarrhea
- Headache or dizziness
- Liver problems
- Swelling or worsening heart failure
Important warnings
- Can cause serious liver injury; symptoms may include yellow skin, dark urine, or unusual tiredness.
- May worsen heart failure; risk is higher with certain doses and conditions.
- Many medicines interact with itraconazole; some combinations can cause dangerous heart rhythm problems.
- Capsules work best after a full meal; stomach-acid medicines can reduce absorption.
Pregnancy
Can harm an unborn baby. Avoid during pregnancy unless treating a serious infection under specialist care; avoid conception during treatment and for two months afterward.
Breastfeeding
Small amounts may enter breast milk; discuss use with a healthcare professional, especially for prolonged treatment.
Interactions
- Some cholesterol medicines, sedatives, heart-rhythm drugs, and blood thinners have dangerous interactions.
- Rifampin, rifabutin, and some seizure medicines can greatly reduce itraconazole levels.
- Antacids and acid-reducing medicines may lower capsule absorption.
- Itraconazole can increase levels of many other medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.