About celecoxib
Selective COX-2 anti-inflammatory (NSAID)
Used for
- Osteoarthritis and rheumatoid arthritis pain and inflammation
- Ankylosing spondylitis
- Short-term acute pain
- Painful menstrual periods
Usual adult dose
Osteoarthritis: 200 mg daily. Rheumatoid arthritis: 100–200 mg twice daily. Other uses vary.
Usual dose in children
Juvenile arthritis, age 2 years and older: 50 mg twice daily if under 25 kg; 100 mg twice daily if 25 kg or more.
Common side effects
- Indigestion, stomach pain, diarrhea
- Headache or dizziness
- Swelling of legs or feet
- Raised blood pressure
Important warnings
- Can increase risk of heart attack or stroke; risk rises with dose and duration.
- Can cause stomach ulcers or bleeding, sometimes without warning.
- Avoid after coronary artery bypass surgery; use caution with heart, kidney, or liver disease.
- Seek urgent care for severe allergic reaction, chest pain, weakness, or black stools.
Pregnancy
Avoid from 20 weeks unless specifically directed; avoid from 30 weeks because of fetal heart risks.
Breastfeeding
Limited information; discuss with a clinician, especially when nursing a newborn or premature infant.
Interactions
- Warfarin and other blood thinners increase bleeding risk.
- Aspirin or other NSAIDs increase stomach and bleeding risks.
- ACE inhibitors, ARBs, or diuretics may worsen kidney function.
- Fluconazole, lithium, and some antidepressants can interact.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.