About eplerenone
Selective aldosterone receptor blocker
Used for
- Heart failure after a heart attack with reduced pumping function
- Chronic heart failure with reduced pumping function
- High blood pressure
Usual adult dose
Heart failure: usually 25 mg once daily, increasing to 50 mg once daily if tolerated. High blood pressure: usually 50 mg once daily.
Common side effects
- High potassium
- Dizziness
- Diarrhea
- Reduced kidney function
Important warnings
- Potassium and kidney function need monitoring.
- Avoid with high potassium or severe kidney disease.
- Risk of high potassium increases with kidney problems, diabetes, and some medicines.
- May cause dizziness, especially when starting treatment.
Pregnancy
Human pregnancy data are limited; use only when clearly needed after clinician assessment.
Breastfeeding
It is unknown whether eplerenone passes into human milk; breastfeeding decisions require clinician assessment.
Interactions
- Potassium supplements and potassium-containing salt substitutes
- ACE inhibitors or ARBs, which can raise potassium
- Strong CYP3A4 inhibitors, such as clarithromycin or ketoconazole
- NSAIDs, which may affect kidney function and potassium
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.