About glyceryl trinitrate
Organic nitrate vasodilator
Used for
- Rapid treatment of angina when given by infusion
- Control of high blood pressure during surgery
- Treatment of heart failure in selected hospital settings
Usual adult dose
Intravenous infusion is individualized, commonly starting at 5–10 micrograms per minute and adjusted under close monitoring.
Common side effects
- Headache
- Low blood pressure or dizziness
- Flushing
- Fast heartbeat
Important warnings
- Requires continuous blood-pressure and heart-rate monitoring.
- Avoid with sildenafil, tadalafil, vardenafil, or riociguat; dangerous blood-pressure drops may occur.
- Use caution with low blood pressure, dehydration, or raised pressure inside the skull.
- This injectable medicine is administered by healthcare professionals.
Pregnancy
Use only when clearly needed; evidence is limited, and treatment requires specialist assessment.
Breastfeeding
Information is limited; use requires clinician assessment.
Interactions
- Phosphodiesterase-5 inhibitors, including sildenafil and tadalafil, can cause severe hypotension.
- Riociguat can cause severe hypotension.
- Other blood-pressure-lowering medicines may increase hypotension.
- Alcohol may worsen dizziness and low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.