About acetaminophen diphenhydramine hydrochloride
Pain reliever and sedating antihistamine
Used for
- Short-term relief of pain that interferes with sleep
- Temporary relief of occasional sleeplessness associated with pain
Usual adult dose
Adults and ages 16+: two caplets at bedtime; follow the local package instructions and do not exceed its daily limit.
Common side effects
- Drowsiness
- Dry mouth
- Blurred vision
- Constipation
Important warnings
- Contains paracetamol; avoid taking other paracetamol-containing medicines.
- Alcohol and other sedatives can increase drowsiness.
- May impair alertness; avoid driving or operating machinery.
- Not intended for prolonged use; diphenhydramine can cause confusion, especially in older adults.
Pregnancy
Avoid unless a healthcare professional advises use; diphenhydramine is generally not recommended for routine sleep problems during pregnancy.
Breastfeeding
Generally avoid: diphenhydramine may affect the infant or milk supply, especially with repeated use.
Interactions
- Alcohol, opioids, and sedatives: increased drowsiness.
- Other antihistamines or anticholinergic medicines: increased side effects.
- Warfarin: regular paracetamol use may increase bleeding risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.