About PRILOCAINE 25 MG/GM
Local anesthetic combination
Used for
- Numbs intact skin before needle procedures or minor skin procedures.
- Numbs genital skin or mucosa before certain procedures.
Usual adult dose
Apply a thick layer under an airtight dressing, usually for 1–2 hours before procedures; genital use varies by procedure.
Usual dose in children
For intact skin, dose and application time depend on age, treated area, and procedure. Avoid use in infants under 12 months taking methemoglobin-causing medicines.
Common side effects
- Temporary skin pallor, redness, swelling, or altered sensation
- Burning or itching at the application site
- Rare allergic reactions
- Rare methemoglobinemia, which reduces oxygen delivery
Important warnings
- Use only on recommended areas and for the recommended duration; excessive use can cause serious toxicity.
- Do not apply to open wounds, eyes, or inside the ear unless specifically directed.
- Risk of methemoglobinemia is higher in young infants and people with certain blood disorders or medicines.
- Avoid use with other local anesthetics unless medically directed.
Pregnancy
Absorption is usually low when used correctly, but pregnancy use should be limited to situations where needed.
Breastfeeding
Generally compatible when used correctly; prevent infant contact with treated skin and avoid application to the nipple.
Interactions
- Medicines that cause methemoglobinemia, including dapsone, sulfonamides, and some nitrates
- Other local anesthetics, which can increase systemic toxicity
- Some antiarrhythmics, including mexiletine, which may add to local-anesthetic effects
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.