About rivaroxaban
Direct factor Xa inhibitor anticoagulant
Used for
- Prevents blood clots after hip or knee replacement surgery
- Treats deep vein thrombosis and pulmonary embolism
- Prevents recurrent deep vein thrombosis or pulmonary embolism
- Prevents stroke in adults with nonvalvular atrial fibrillation
Usual adult dose
Common regimens: 10 mg once daily after hip or knee replacement; 15 mg twice daily for 21 days, then 20 mg daily for acute DVT or PE. Other uses require different doses.
Usual dose in children
For children with blood clots, dosing depends on age, weight, and treatment; specialist prescribing is required.
Common side effects
- Bleeding or easy bruising
- Anemia
- Nausea
- Stomach or back pain
Important warnings
- Can cause serious or fatal bleeding; seek urgent care for uncontrolled bleeding.
- Do not stop suddenly without medical direction; clot or stroke risk may increase.
- Spinal or epidural procedures can cause dangerous bleeding around the spine.
- Dose may need adjustment or avoidance with kidney or liver disease.
Pregnancy
May cause harm, including bleeding; generally avoided during pregnancy unless a specialist determines benefits outweigh risks.
Breastfeeding
It is unknown whether rivaroxaban passes into human milk; use requires clinician review.
Interactions
- Other blood thinners and antiplatelet medicines increase bleeding risk.
- NSAIDs such as ibuprofen can increase bleeding risk.
- Some antifungal and HIV medicines raise rivaroxaban levels.
- Rifampin, carbamazepine, phenytoin, and St John’s wort may reduce its effect.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.