About nelfinavir mesilate
HIV protease inhibitor
Used for
- Treatment of HIV-1 infection with other antiretroviral medicines
Usual adult dose
Usually 1,250 mg by mouth twice daily or 750 mg three times daily, with food.
Usual dose in children
For children aged 2 years and older: dose by weight or body surface area, with food; specialist dosing is required.
Common side effects
- Diarrhea
- Nausea
- Rash
- Abnormal blood sugar or cholesterol
Important warnings
- Not a cure for HIV; combination treatment is required.
- Can cause serious allergic skin reactions or liver problems.
- May worsen blood sugar and cholesterol levels.
- Many medicines interact; some combinations can cause dangerous effects.
Pregnancy
Use only when the expected benefit outweighs potential risks; treatment choice requires specialist review.
Breastfeeding
People with HIV should generally not breastfeed because HIV can pass to the infant.
Interactions
- Rifampin and St. John’s wort can greatly reduce nelfinavir levels.
- Certain statins, sedatives, and heart-rhythm medicines can reach dangerous levels.
- Nelfinavir can interact with many HIV medicines and other drugs.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.