About alendronate sodium + cholecalciferol
Bisphosphonate and vitamin D combination
Used for
- Treats and prevents osteoporosis after menopause.
- Treats osteoporosis in men.
- Treats osteoporosis caused by long-term corticosteroid use.
Usual adult dose
One tablet once weekly, taken fasting with plain water.
Common side effects
- Heartburn or indigestion
- Stomach or abdominal pain
- Muscle, joint, or bone pain
- Nausea
Important warnings
- Can irritate the esophagus; swallow whole with water and remain upright for 30 minutes.
- Avoid with swallowing problems, low blood calcium, or inability to sit or stand upright.
- Rarely causes jawbone problems or unusual thigh fractures, especially with prolonged use.
- Not suitable for severe kidney impairment or significant vitamin D excess.
Pregnancy
Not recommended during pregnancy; safety is not established.
Breastfeeding
Not recommended while breastfeeding; safety is not established.
Interactions
- Calcium, antacids, and mineral supplements reduce absorption; separate by at least 30 minutes.
- Food, coffee, and other drinks reduce absorption; take with plain water only.
- NSAIDs may increase stomach irritation.
- Other vitamin D supplements can increase vitamin D intake.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.