About cenobamate
Antiseizure medication
Used for
- Treatment of partial-onset (focal) seizures in adults.
Usual adult dose
Start 12.5 mg once daily; increase every two weeks to 200 mg daily. If needed, increase gradually to 400 mg daily.
Common side effects
- Sleepiness, dizziness, and fatigue
- Double vision or headache
- Nausea or constipation
- Coordination problems
Important warnings
- Increase dose gradually; sudden stopping may increase seizure risk.
- Can cause serious allergic reactions, including DRESS, especially early in treatment.
- May shorten the QT interval; avoid with familial short-QT syndrome.
- Can cause suicidal thoughts or mood changes.
Pregnancy
May harm an unborn baby; pregnancy registry information is available. Discuss pregnancy plans with a healthcare professional.
Breastfeeding
It is unknown whether cenobamate passes into breast milk or affects a nursing infant.
Interactions
- Can reduce hormonal contraceptive effectiveness; use additional or alternative contraception.
- May increase effects of phenytoin, phenobarbital, or clobazam.
- Alcohol and other sedatives may worsen sleepiness and dizziness.
- May lower levels of some medicines, including warfarin and certain oral contraceptives.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.