About ethacrynic acid
Loop diuretic
Used for
- Treats fluid buildup from heart failure, liver disease, or kidney disease.
- May be used for high blood pressure.
Usual adult dose
Usually 50–200 mg by mouth daily, adjusted to response; higher doses may be divided.
Usual dose in children
Usually 1–2 mg/kg by mouth daily; dose is adjusted by response.
Common side effects
- Frequent urination, dizziness, or low blood pressure
- Low potassium, sodium, or magnesium
- Dehydration or worsening kidney function
- Nausea, diarrhea, or hearing problems
Important warnings
- Can cause dehydration and serious electrolyte changes.
- Hearing damage is more likely with high doses or kidney problems.
- Use cautiously with impaired kidney or liver function.
- Seek urgent care for severe weakness, fainting, or reduced urination.
Pregnancy
Use only when clearly needed; available pregnancy safety information is limited.
Breastfeeding
It is not known whether ethacrynic acid enters breast milk; effects on milk supply are possible.
Interactions
- Other drugs that damage hearing, such as aminoglycoside antibiotics
- Lithium, which may reach harmful levels
- Digoxin, with increased risk from low potassium
- Other blood pressure medicines, which may increase dizziness
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.