About bortezomi b
Proteasome inhibitor anticancer medicine
Used for
- Treats multiple myeloma, alone or with other cancer medicines.
- Treats mantle cell lymphoma, usually with other medicines.
Usual adult dose
Usually 1.3 mg/m² by intravenous injection or under the skin, on treatment days in cycles. Schedule depends on the condition and treatment plan.
Common side effects
- Low blood cell counts, including platelets and red cells
- Numbness, tingling, or pain in hands and feet
- Nausea, diarrhea, constipation, or vomiting
- Fatigue, fever, or shingles
Important warnings
- Can cause serious infections, bleeding, nerve damage, or heart problems.
- May cause low blood pressure or tumor lysis syndrome.
- Avoid spinal injection; use only by the prescribed route.
- Dosing and monitoring require an oncology team.
Pregnancy
May harm an unborn baby. Avoid pregnancy during treatment; effective contraception is important.
Breastfeeding
Breastfeeding is not recommended during treatment.
Interactions
- Strong CYP3A4 inhibitors or inducers may alter bortezomib levels.
- Rifampin can reduce its effectiveness; avoid combination.
- Medicines affecting blood sugar may require closer monitoring.
- Other medicines that lower blood counts or cause nerve damage may increase risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.