About INSULIN GLARGINE 100U/ML + LIXISENATIDE 33MCG/ML
Basal insulin and GLP-1 receptor agonist combination
Used for
- Improves blood sugar control in adults with type 2 diabetes, alongside diet and exercise.
Usual adult dose
Injected under the skin once daily within one hour before the first meal. The prescribed dose is individualized and adjusted by blood glucose response.
Common side effects
- Low blood sugar
- Nausea, vomiting, or diarrhea
- Injection-site reactions
- Headache
Important warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Can cause severe low blood sugar, especially with other diabetes medicines.
- Not recommended in severe gastroparesis; may cause dehydration from vomiting or diarrhea.
- Use caution with pancreatitis history; seek urgent care for persistent severe abdominal pain.
Pregnancy
Insulin may be used during pregnancy, but this combination has limited pregnancy data. A clinician should manage treatment and blood glucose closely.
Breastfeeding
Insulin is generally compatible with breastfeeding; information on lixisenatide is limited. Treatment should be reviewed with a clinician.
Interactions
- Other glucose-lowering medicines can increase low blood sugar risk.
- May slow stomach emptying and affect absorption of oral medicines.
- Some oral medicines may need to be taken at least one hour before injection.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.