About cefixime as trihydrate
Third-generation cephalosporin antibiotic
Used for
- Treats certain bacterial infections, including urinary, ear, throat, and chest infections.
- May treat gonorrhea when recommended by local guidelines.
Usual adult dose
Usually 400 mg once daily or 200 mg every 12 hours; duration depends on infection.
Usual dose in children
For children 6 months and older: usually 8 mg/kg daily, once or divided every 12 hours; maximum 400 mg daily.
Common side effects
- Diarrhea, nausea, or stomach discomfort
- Rash or itching
- Headache
- Rarely, severe allergic reaction or severe diarrhea
Important warnings
- Does not treat viral infections such as colds or flu.
- Avoid with serious allergy to cefixime or other cephalosporins.
- Dose may need adjustment in kidney impairment.
- Seek urgent care for breathing difficulty, facial swelling, or severe skin reactions.
Pregnancy
Generally used when needed; available human data have not established a clear risk. Prescriber weighs benefits and risks.
Breastfeeding
Small amounts may enter breast milk; usually compatible, but monitor the infant for diarrhea or rash.
Interactions
- Warfarin and other anticoagulants: may increase bleeding or affect clotting tests.
- Carbamazepine: cefixime may increase carbamazepine levels.
- Probenecid may increase cefixime levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.