About lisdexamfetamine mesilate
Central nervous system stimulant
Used for
- Attention-deficit/hyperactivity disorder (ADHD)
- Moderate to severe binge-eating disorder in adults
Usual adult dose
ADHD: usually 30 mg once each morning; adjust weekly. Binge-eating disorder: start 30 mg each morning, usually target 50–70 mg daily.
Usual dose in children
ADHD, ages 6 and older: usually 30 mg each morning; adjust weekly. Not approved for children under 6.
Common side effects
- Reduced appetite and weight loss
- Difficulty sleeping
- Dry mouth
- Increased heart rate or blood pressure
Important warnings
- Risk of misuse, dependence, and overdose
- May worsen heart problems or raise blood pressure
- Can trigger or worsen psychiatric symptoms
- Avoid with monoamine oxidase inhibitors or within 14 days of stopping them
Pregnancy
May cause fetal harm; use in pregnancy requires careful medical assessment.
Breastfeeding
Not recommended during breastfeeding; lisdexamfetamine and its active metabolite may enter breast milk.
Interactions
- Monoamine oxidase inhibitors can cause dangerous blood-pressure increases
- Serotonergic medicines may increase serotonin syndrome risk
- Urinary alkalinizers may increase effects; acidifiers may reduce them
- Other stimulants can increase cardiovascular and nervous-system effects
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.