About irbesartan
Angiotensin II receptor blocker
Used for
- High blood pressure
- Kidney disease in adults with type 2 diabetes and high blood pressure
Usual adult dose
Usually 150 mg once daily for high blood pressure; 300 mg once daily may be used. For diabetic kidney disease, usually 300 mg once daily.
Usual dose in children
For ages 6–16 with high blood pressure: usually 75 mg once daily; doses may be increased up to 300 mg daily.
Common side effects
- Dizziness
- Low blood pressure
- High potassium
- Changes in kidney function
Important warnings
- Can cause serious harm or death to an unborn baby; avoid during pregnancy.
- Monitor blood pressure, kidney function, and potassium, especially after starting or increasing dose.
- Use caution with dehydration, kidney artery narrowing, or severe heart failure.
- Do not combine with aliskiren in people with diabetes.
Pregnancy
Avoid during pregnancy. Stop as soon as pregnancy is detected; fetal kidney injury and death can occur.
Breastfeeding
Limited information is available; use an alternative, especially when nursing a newborn or premature infant.
Interactions
- Potassium supplements or salt substitutes may raise potassium.
- NSAIDs, including ibuprofen, may worsen kidney function and reduce blood-pressure control.
- Lithium levels and toxicity may increase.
- ACE inhibitors or aliskiren can increase low blood pressure, high potassium, and kidney injury risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.