About tadalafil
Phosphodiesterase-5 inhibitor
Used for
- Erectile dysfunction
- Pulmonary arterial hypertension, under specialist care
- Benign prostate enlargement, usually with erectile dysfunction
Usual adult dose
Erectile dysfunction: 10 mg before sex, adjusted to 5–20 mg; no more than once daily. Prostate symptoms: 5 mg daily. Pulmonary hypertension dosing differs by product and specialist plan.
Common side effects
- Headache
- Indigestion
- Flushing
- Back or muscle pain
Important warnings
- Do not use with nitrate medicines or riociguat; blood pressure may fall dangerously.
- Seek urgent care for an erection lasting over four hours or sudden vision or hearing loss.
- Use cautiously with heart disease, low blood pressure, or severe kidney or liver problems.
- Avoid grapefruit; alcohol can increase dizziness and blood-pressure lowering.
Pregnancy
Not indicated for women; use during pregnancy is generally limited to specialist-directed pulmonary hypertension treatment.
Breastfeeding
Not indicated for routine use while breastfeeding; specialist advice is needed for pulmonary hypertension.
Interactions
- Nitrates, riociguat, and some recreational nitrites can cause dangerous blood-pressure drops.
- Alpha-blockers and blood-pressure medicines may increase dizziness or low blood pressure.
- Strong CYP3A4 inhibitors, such as ritonavir, can raise tadalafil levels.
- Other erectile dysfunction medicines may increase side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.