About human normal immunoglo
Subcutaneous immunoglobulin replacement therapy
Used for
- Replacement treatment for primary immunodeficiency
- Replacement treatment for certain secondary immunodeficiencies
Usual adult dose
Individualized; usually 0.2–0.5 g/kg weekly, adjusted to clinical response and IgG levels.
Usual dose in children
Individualized; usually 0.2–0.5 g/kg weekly for children with primary immunodeficiency.
Common side effects
- Injection-site pain, swelling, redness, or itching
- Headache
- Nausea
- Fatigue
Important warnings
- Rare serious allergic reactions can occur, especially with IgA deficiency and anti-IgA antibodies.
- Rare blood clots, kidney problems, or red-cell breakdown may occur.
- Seek urgent care for breathing difficulty, chest pain, sudden weakness, or severe headache.
- Do not inject into a blood vessel.
Pregnancy
Use when clinically needed; pregnancy safety data are limited. Maternal immunoglobulin may cross the placenta.
Breastfeeding
Immunoglobulin is present naturally in breast milk; treatment is generally considered compatible with breastfeeding.
Interactions
- May interfere with live vaccines, including measles, mumps, rubella, and varicella vaccines.
- May affect the interpretation of some blood tests, including antibody-based tests.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.