About diacerein
Osteoarthritis symptom-modifying medicine
Used for
- Relief of symptoms in osteoarthritis, especially of the knee or hip.
Usual adult dose
Usually 50 mg once daily for 2–4 weeks, then 50 mg twice daily with meals.
Common side effects
- Diarrhea, sometimes severe
- Abdominal pain or indigestion
- Dark urine
- Raised liver enzymes
Important warnings
- Can cause severe diarrhea and dehydration; treatment may need stopping.
- Rarely causes liver injury; avoid with liver disease.
- Not recommended for people aged 65 years or older in some regions.
- Benefit may take several weeks to appear.
Pregnancy
Generally avoid; safety information is limited.
Breastfeeding
Generally avoid; whether it passes into breast milk is uncertain.
Interactions
- Laxatives may worsen diarrhea.
- Antacids can reduce absorption; separate doses by at least two hours.
- Use caution with medicines that can affect the liver.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.