About Human hepatitis B immunoglobulin
for intravenous administration
50IU/ml
Human hepatitis B immunoglobulin
Used for
- Prevents hepatitis B after exposure, including needlestick injury or contact with infected blood.
- Prevents hepatitis B recurrence after liver transplantation in people with chronic hepatitis B.
- Prevents infection in babies born to mothers with hepatitis B, alongside vaccination.
Usual adult dose
Dose and infusion schedule depend on the reason for use; specialist protocols are required, especially after transplantation.
Usual dose in children
For newborns exposed at birth, dosing follows specialist protocols and is given with hepatitis B vaccine.
Common side effects
- Headache, fever, chills, nausea, or vomiting
- Infusion reactions, including flushing or changes in blood pressure
- Allergic reactions, rarely severe
- Blood clots or kidney problems, rarely
Important warnings
- Must be given by intravenous infusion under medical supervision.
- Severe allergic reactions can occur, especially with IgA deficiency and anti-IgA antibodies.
- Blood products carry a small residual risk of transmitting infections.
- Infusion speed may need adjustment if reactions occur.
Pregnancy
May be used when clinically necessary; available evidence has not identified a known risk to pregnancy.
Breastfeeding
Use when clinically necessary; immunoglobulins are expected to pose little risk during breastfeeding.
Interactions
- May reduce responses to live vaccines, such as measles, mumps, rubella, and varicella; vaccination may need delaying.
- Can interfere with some blood tests, including tests for antibodies to infections.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.