About oxycodone hcl
Extended-release opioid pain medicine
Used for
- Severe ongoing pain requiring around-the-clock opioid treatment when other options are inadequate.
Usual adult dose
Usually 10 mg by mouth every 12 hours initially; doses are individualized and increased cautiously.
Usual dose in children
For opioid-tolerant children aged 11 years and older: individualized every 12 hours; specialist supervision is required.
Common side effects
- Constipation
- Nausea and vomiting
- Drowsiness and dizziness
- Itching
Important warnings
- Can cause fatal breathing problems, especially when starting or increasing doses.
- Dependence, addiction, and overdose are possible; keep securely stored.
- Swallow tablets whole; crushing or chewing can release a dangerous dose.
- Avoid alcohol and use caution with sedatives or breathing disorders.
Pregnancy
May cause newborn withdrawal after prolonged use; opioid use near delivery can also affect newborn breathing.
Breastfeeding
Not recommended; oxycodone can pass into milk and cause serious infant sleepiness or breathing problems.
Interactions
- Benzodiazepines and other sedatives can cause profound sedation or fatal breathing suppression.
- Alcohol increases sedation and overdose risk.
- Strong CYP3A4 inhibitors or inducers can substantially alter oxycodone levels.
- Serotonergic medicines may increase serotonin syndrome risk.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.