About basiliximab
Interleukin-2 receptor antagonist immunosuppressant
Used for
- Prevention of acute kidney transplant rejection, with other immunosuppressive medicines
Usual adult dose
Adults: 20 mg intravenously on transplant day and again four days later.
Usual dose in children
Children weighing 35 kg or more: 20 mg intravenously on transplant day and day four. Below 35 kg: 10 mg on each day.
Common side effects
- Constipation, nausea, or vomiting
- High blood pressure
- Headache or tremor
- Infections
Important warnings
- Given by specialist teams in transplant settings.
- Severe allergic reactions can occur during or shortly after infusion.
- Infection risk may increase with other immunosuppressants.
- Do not give the second dose if a severe hypersensitivity reaction occurs.
Pregnancy
Use during pregnancy only if clearly needed; human pregnancy data are limited.
Breastfeeding
It is not known whether basiliximab passes into breast milk; discuss risks with a clinician.
Interactions
- Other immunosuppressants may increase infection risk.
- Live vaccines may be less effective or unsafe during immunosuppressive treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.