About trisodium citrate
Anticoagulant catheter-lock solution
Used for
- Locks dialysis and other vascular catheters to help prevent clotting while not in use.
Usual adult dose
Instill only the catheter’s specified internal volume after dialysis or as directed by its protocol; withdraw before use.
Usual dose in children
Instill only the catheter’s specified internal volume under a pediatric catheter protocol; withdraw before use.
Common side effects
- Bleeding or bruising if solution enters the bloodstream
- Low blood calcium, potentially causing tingling, cramps, or abnormal heart rhythms
- Catheter blockage or infection
Important warnings
- For catheter locking only; never inject into a vein as a systemic dose.
- Use the exact catheter fill volume and withdraw the lock before catheter use.
- Accidental systemic entry can cause severe low calcium and heart rhythm problems.
- Use sterile technique; citrate does not prevent catheter-related infection.
Pregnancy
Systemic exposure is not intended when used correctly as a catheter lock; pregnancy-specific data are limited.
Breastfeeding
Systemic exposure is not intended when used correctly as a catheter lock; breastfeeding-specific data are limited.
Interactions
- Systemic anticoagulants may increase bleeding risk if citrate enters the bloodstream.
- Other citrate-containing products can add to citrate exposure if absorbed systemically.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.