About estradiol as hemihydra
Estrogen-progestogen hormone replacement therapy
Used for
- Relief of menopausal symptoms in women with a uterus.
- Prevention of osteoporosis after menopause when other treatments are unsuitable.
Usual adult dose
One tablet once daily, taken continuously; prescribed for postmenopausal women with a uterus.
Common side effects
- Headache, nausea, abdominal pain, or breast tenderness.
- Irregular vaginal bleeding or spotting.
- Fluid retention or mood changes.
- Serious risks include blood clots, stroke, and certain cancers.
Important warnings
- Not for pregnancy or unexplained vaginal bleeding.
- Avoid with current or previous breast cancer, blood clots, stroke, or severe liver disease.
- Hormone therapy can increase breast cancer risk with longer use.
- Seek urgent care for chest pain, sudden breathlessness, or one-sided leg swelling.
Pregnancy
Not for use during pregnancy; stop if pregnancy occurs.
Breastfeeding
Not indicated during breastfeeding; estrogen may reduce milk production.
Interactions
- Some seizure medicines, rifampicin, and St John’s wort can reduce hormone effects.
- Some HIV or hepatitis medicines may alter hormone levels.
- Hormone therapy can affect blood clotting medicines such as warfarin.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.