About Gloclav 1gm Tablets
Penicillin antibiotic with beta-lactamase inhibitor
Used for
- Bacterial sinus, ear, and respiratory infections
- Urinary tract infections
- Skin and soft-tissue infections
- Dental infections
Usual adult dose
Commonly 500/125 mg every 8 hours or 875/125 mg every 12 hours, depending on infection.
Usual dose in children
Usually 25–45 mg/kg/day of amoxicillin, divided every 12 hours; dose depends on infection and formulation.
Common side effects
- Diarrhea
- Nausea or vomiting
- Skin rash
- Thrush
Important warnings
- Not effective against viral infections.
- Avoid with serious penicillin allergy.
- Can cause severe allergic reactions or antibiotic-associated diarrhea.
- Liver injury is uncommon but possible; previous related jaundice is a contraindication.
Pregnancy
Generally considered acceptable when prescribed; available safety data have not shown a clear increase in birth defects.
Breastfeeding
Usually compatible; monitor the infant for diarrhea, rash, or thrush.
Interactions
- Warfarin and other anticoagulants: may alter bleeding tests.
- Allopurinol: may increase risk of skin rash.
- Probenecid: increases amoxicillin levels.
- Methotrexate: may increase methotrexate exposure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.