About enzalutamide
Androgen receptor inhibitor
Used for
- Treats prostate cancer that has spread or is at high risk of spreading.
- Used in several advanced prostate cancer settings, often with hormone-lowering treatment.
Usual adult dose
160 mg by mouth once daily; capsules may be taken with or without food.
Common side effects
- Tiredness
- Hot flushes
- High blood pressure
- Falls or fractures
Important warnings
- May cause seizures, rarely; risk is higher with certain brain conditions or medicines.
- Can cause serious falls, fractures, or heart problems.
- May harm an unborn baby; use effective contraception during treatment and afterward.
- Do not stop hormone-lowering treatment unless the prescriber directs.
Pregnancy
Not for use during pregnancy; may harm an unborn baby. Men with partners who could become pregnant should use contraception during treatment and for three months afterward.
Breastfeeding
Not indicated for women; breastfeeding safety is unknown.
Interactions
- Can reduce effectiveness of many medicines, including some blood thinners, seizure medicines, and hormonal contraceptives.
- Some medicines can raise or lower enzalutamide levels; examples include strong CYP2C8 or CYP3A4 modifiers.
- Check all prescription medicines, over-the-counter products, and supplements for interactions.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.