About factor viii
Plasma-derived coagulation factor VIII
Used for
- Treatment and prevention of bleeding in haemophilia A
- Prevention of bleeding during surgery in haemophilia A
Usual adult dose
Dose is individualized by bleed severity, target factor level, and recovery; commonly 20–50 IU/kg per dose.
Usual dose in children
Dose is individualized by bleed severity and measured factor levels; commonly 20–50 IU/kg per dose.
Common side effects
- Allergic reactions, including rash or itching
- Headache, dizziness, or fever
- Injection-site reactions
- Development of factor VIII inhibitors
Important warnings
- Severe allergic reactions can occur, especially with inhibitors.
- Monitor factor VIII levels and inhibitor development during treatment.
- Reduced response may indicate an inhibitor; specialist assessment is required.
- Use only the prescribed product and follow its preparation instructions.
Pregnancy
Limited data; use when clinically necessary under specialist supervision.
Breastfeeding
Limited data; use when clinically necessary under specialist supervision.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.