About pentaerithrityl tetranitrate
Long-acting organic nitrate vasodilator
Used for
- Prevention of angina (chest pain) due to coronary artery disease
Usual adult dose
Usually 50 mg by mouth two or three times daily; dosing varies by product and patient.
Common side effects
- Headache
- Dizziness or light-headedness
- Flushing
- Low blood pressure
Important warnings
- Can cause fainting, especially when standing or with alcohol.
- Do not combine with sildenafil, tadalafil, vardenafil, or riociguat; blood pressure may fall dangerously.
- Not for rapid relief of sudden chest pain.
- Regular use may reduce effectiveness; follow prescribed dosing intervals.
Pregnancy
Safety is not well established; use only when a clinician considers it necessary.
Breastfeeding
Safety is not well established; use only when a clinician considers it necessary.
Interactions
- Sildenafil, tadalafil, vardenafil, or riociguat: dangerous blood-pressure drop.
- Other nitrates: increased risk of low blood pressure.
- Alcohol and blood-pressure-lowering medicines: may worsen dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.