About chlorpromazine hydrochloride
First-generation antipsychotic (phenothiazine)
Used for
- Schizophrenia and other psychotic disorders
- Severe nausea and vomiting
- Short-term control of severe agitation
- Hiccups that have not responded to other treatment
Usual adult dose
Varies by condition; commonly 25–100 mg by mouth three times daily for psychosis, adjusted by response.
Usual dose in children
Specialist-directed dosing based on age and weight; not suitable for routine self-treatment.
Common side effects
- Sleepiness, dizziness, and impaired coordination
- Dry mouth, constipation, and blurred vision
- Low blood pressure when standing
- Movement problems, including tremor or muscle stiffness
Important warnings
- Can cause serious movement disorders and, rarely, neuroleptic malignant syndrome.
- May prolong the heart rhythm and increase fainting risk.
- Avoid alcohol; use caution with driving and sedating medicines.
- Older adults with dementia-related psychosis have increased risk of death.
Pregnancy
Use only when clearly needed; treatment near delivery may cause newborn movement or feeding problems.
Breastfeeding
May cause infant sleepiness or poor feeding; seek clinical guidance before use.
Interactions
- Alcohol, opioids, and sedatives can increase drowsiness.
- Medicines that prolong the heart rhythm can raise abnormal-rhythm risk.
- Levodopa and dopamine agonists may have reduced effects.
- Anticholinergic medicines can worsen constipation, blurred vision, or urinary retention.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.