About fluorouracil
Topical antimetabolite chemotherapy
Used for
- Treats actinic keratoses and superficial basal cell skin cancer.
Usual adult dose
Apply a thin layer once or twice daily for several weeks, as prescribed; duration depends on the condition and site.
Common side effects
- Redness, soreness, burning, itching, and skin inflammation.
- Crusting, erosion, or ulceration where applied.
- Skin may become more sensitive to sunlight.
Important warnings
- For skin use only; avoid eyes, mouth, and other mucous membranes.
- Treated skin can become very inflamed; follow the prescribed treatment duration.
- Avoid excessive sunlight and protect treated areas during treatment.
- Do not use during pregnancy; fluorouracil can harm an unborn baby.
Pregnancy
Avoid use during pregnancy because fluorouracil may cause fetal harm.
Breastfeeding
Breastfeeding safety is uncertain; use requires clinician assessment, and application to the breast should be avoided.
Interactions
- Other topical medicines on the same area may increase irritation.
- Brivudine or sorivudine can dangerously increase fluorouracil effects; avoid concurrent use.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.