About desvenlaf axine
Serotonin-norepinephrine reuptake inhibitor (SNRI)
Used for
- Treatment of major depressive disorder in adults
Usual adult dose
Usually 50 mg once daily, with or without food; doses above 50 mg have not shown additional benefit for most patients.
Common side effects
- Nausea
- Dizziness
- Insomnia
- Increased sweating
Important warnings
- May increase suicidal thoughts or behavior, especially in younger people.
- Can cause serotonin syndrome, particularly with other serotonergic medicines.
- Do not stop suddenly; withdrawal symptoms may occur.
- May raise blood pressure; use caution with bipolar disorder or seizure history.
Pregnancy
Use only when the expected benefit outweighs potential risks; late-pregnancy exposure may cause newborn complications.
Breastfeeding
Passes into breast milk; effects on nursing infants are uncertain.
Interactions
- Other serotonergic medicines, including MAO inhibitors, raise serotonin syndrome risk.
- Blood thinners and NSAIDs may increase bleeding risk.
- Some medicines affecting CYP2D6 can alter desvenlafaxine levels.
- Alcohol may worsen side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.