About atazanavir sulfate
HIV protease inhibitor
Used for
- Used with other medicines to treat HIV-1 infection.
Usual adult dose
Usually 300 mg once daily with ritonavir 100 mg, taken with food; regimen varies with other medicines.
Usual dose in children
For children aged 6 years and older, dose is based on weight and taken with ritonavir and food.
Common side effects
- Yellowing of skin or eyes
- Nausea, vomiting, or diarrhea
- Headache
- Kidney stones or gallstones
Important warnings
- Can cause abnormal heart rhythm or serious liver problems.
- May cause kidney stones or gallstones.
- Can raise blood sugar and cholesterol.
- Do not use with certain medicines due to dangerous interactions.
Pregnancy
Dose and regimen may need adjustment during pregnancy; specialist monitoring is recommended.
Breastfeeding
People with HIV should generally not breastfeed where safe alternatives are available, to prevent HIV transmission.
Interactions
- Acid-reducing medicines can lower atazanavir levels.
- Many medicines interact, including some statins, sedatives, and heart medicines.
- Rifampin and St John’s wort can reduce effectiveness.
- Ritonavir or cobicistat alters interactions and dosing.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.