About Danset 4mg/2ml IM/IV Solution for Injection
5-HT3 receptor antagonist antiemetic
Used for
- Prevention and treatment of nausea and vomiting caused by chemotherapy
- Prevention and treatment of nausea and vomiting after surgery
Usual adult dose
Usually 4 mg by injection for postoperative nausea; chemotherapy doses vary by regimen.
Usual dose in children
For chemotherapy, usually 0.15 mg/kg per dose intravenously, up to three doses; age and regimen matter.
Common side effects
- Headache
- Constipation
- Flushing
- Injection-site reactions
Important warnings
- May prolong the heart’s QT interval and rarely cause serious rhythm problems.
- Avoid with apomorphine because severe low blood pressure and loss of consciousness can occur.
- Use caution with congenital long QT syndrome or abnormal blood salts.
- Can mask signs of bowel obstruction after abdominal surgery.
Pregnancy
May be used when clinically needed; discuss benefits and risks with a healthcare professional.
Breastfeeding
Information is limited; use requires consideration of potential benefits and risks.
Interactions
- Apomorphine: risk of severe hypotension and loss of consciousness.
- Other QT-prolonging medicines may increase abnormal heart rhythm risk.
- Serotonergic medicines may rarely contribute to serotonin syndrome.
- Strong enzyme-inducing medicines, such as rifampicin, can lower ondansetron levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.