About pizotifen maleate
Serotonin antagonist; migraine preventive
Used for
- Prevention of migraine attacks, including recurrent migraine.
- Prevention of cluster headaches in some countries.
Usual adult dose
Usually 0.5 mg at night initially, increased gradually; common maintenance is 1.5 mg daily, divided or taken at night.
Usual dose in children
For children aged 2 years and older: usually 0.5 mg at night initially, increased gradually; dosing varies by age and local guidance.
Common side effects
- Drowsiness and fatigue
- Increased appetite and weight gain
- Dry mouth
- Dizziness or nausea
Important warnings
- May impair alertness; avoid driving if drowsy.
- Can cause weight gain; use caution with obesity.
- Use caution with glaucoma, urinary retention, or liver problems.
- Not for treating an acute migraine attack.
Pregnancy
Use only when clearly needed; discuss risks and benefits with a clinician. Pregnancy data are limited.
Breastfeeding
May pass into breast milk and could affect milk supply or cause infant drowsiness; seek clinical guidance.
Interactions
- Alcohol and sedatives can increase drowsiness.
- Other medicines causing drowsiness may intensify this effect.
- Some antidepressants may increase drowsiness or other side effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.