About nicorandil
Anti-anginal vasodilator
Used for
- Prevention of angina (chest pain) when other treatments are inadequate or unsuitable.
Usual adult dose
Usually 10–20 mg twice daily; adjusted to response and tolerability.
Common side effects
- Headache, especially when starting treatment
- Dizziness or weakness
- Flushing
- Nausea
Important warnings
- Can cause serious ulcers in the mouth, gut, skin, or eyes; seek urgent assessment for possible ulcers.
- Do not use for sudden angina attacks.
- May lower blood pressure and cause dizziness or fainting.
- Avoid if you have low blood pressure or certain heart conditions.
Pregnancy
Use only if clearly needed; human pregnancy information is limited.
Breastfeeding
Avoid during breastfeeding unless a clinician determines it is necessary; information is limited.
Interactions
- Do not combine with sildenafil, tadalafil, vardenafil, or other PDE-5 inhibitors.
- Avoid riociguat because severe blood-pressure reduction may occur.
- Blood-pressure-lowering medicines and alcohol may increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.