About darunavir ethanolate
HIV protease inhibitor
Used for
- Treatment of HIV-1 infection, with other antiretroviral medicines.
Usual adult dose
Usually 800 mg once daily with ritonavir or cobicistat; some patients need 600 mg twice daily with ritonavir.
Usual dose in children
For children aged 3 years and older, dose is based on weight and must be combined with ritonavir; regimens vary.
Common side effects
- Diarrhea, nausea, vomiting, or abdominal pain
- Rash
- Headache
- Increased liver enzymes or cholesterol
Important warnings
- Must be taken with food and a boosting medicine, as prescribed.
- Can cause serious liver problems or severe skin reactions.
- May worsen diabetes or increase bleeding risk in people with hemophilia.
- Does not prevent HIV transmission; continue safer-sex practices.
Pregnancy
Use during pregnancy only under specialist guidance; treatment choices and dosing may differ.
Breastfeeding
People with HIV should generally not breastfeed, because HIV can pass to the infant.
Interactions
- Many medicines interact; check before starting or stopping any medicine.
- Do not combine with rifampin, St John’s wort, or certain cholesterol medicines.
- Can interact with hormonal contraceptives and some seizure medicines.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.