About tizanidine hcl
Centrally acting muscle relaxant
Used for
- Short-term relief of painful muscle spasms
- Treatment of spasticity from multiple sclerosis or spinal cord injury
Usual adult dose
Spasms: 2–4 mg up to three times daily. Spasticity: start 2 mg three times daily; increase gradually, maximum 36 mg daily.
Common side effects
- Sleepiness or dizziness
- Dry mouth
- Weakness or fatigue
- Low blood pressure
Important warnings
- May cause severe drowsiness; avoid driving if affected.
- Do not stop long-term treatment suddenly; taper gradually.
- Liver injury can occur; monitoring may be needed.
- Use cautiously with kidney problems or low blood pressure.
Pregnancy
Use only if clearly needed; human pregnancy information is limited.
Breastfeeding
Not recommended because information on safety during breastfeeding is limited.
Interactions
- Fluvoxamine and ciprofloxacin can dangerously increase tizanidine levels; avoid together.
- Alcohol, opioids, and sedatives can increase drowsiness.
- Blood-pressure medicines may increase low blood pressure.
- Other medicines affecting liver enzymes may alter its levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.