About nesiritide
Recombinant B-type natriuretic peptide
Used for
- Short-term treatment of adults with acutely decompensated heart failure and breathlessness at rest or minimal activity.
Usual adult dose
Intravenous 2 micrograms/kg bolus, then 0.01 micrograms/kg/min infusion; clinicians may omit the bolus or adjust the infusion.
Common side effects
- Low blood pressure
- Dizziness
- Headache
- Nausea
Important warnings
- Can cause severe or prolonged low blood pressure.
- Use only with close blood-pressure monitoring in a hospital.
- May worsen kidney function; monitor kidney status and urine output.
- Avoid in cardiogenic shock or when blood pressure is already very low.
Pregnancy
Use only when clearly needed; human pregnancy data are limited.
Breastfeeding
It is unknown whether nesiritide passes into breast milk; use caution.
Interactions
- Other blood-pressure-lowering medicines can increase the risk of low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.