About erlotinib
Epidermal growth factor receptor inhibitor
Used for
- Treats certain advanced or metastatic non-small-cell lung cancers
- Treats pancreatic cancer with gemcitabine
Usual adult dose
Usually 150 mg once daily for lung cancer; 100 mg once daily with gemcitabine for pancreatic cancer.
Common side effects
- Rash
- Diarrhea
- Loss of appetite
- Fatigue
Important warnings
- Can cause serious lung inflammation, liver injury, or gastrointestinal perforation.
- Avoid smoking; it can reduce erlotinib levels and effectiveness.
- Take on an empty stomach, at least one hour before or two hours after food.
- Seek urgent care for severe breathing problems, persistent diarrhea, or eye pain.
Pregnancy
May harm an unborn baby. Effective contraception is recommended during treatment and for one month after the last dose.
Breastfeeding
Breastfeeding is not recommended during treatment and for two weeks after the last dose.
Interactions
- Strong CYP3A4 inhibitors or inducers can alter erlotinib levels.
- Acid-reducing medicines, including proton-pump inhibitors, can lower absorption.
- Warfarin may increase bleeding risk; monitor closely.
- Grapefruit may affect drug levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.