About interferon gamma b
Recombinant interferon immunomodulator
Used for
- Reduces serious infections in chronic granulomatous disease.
- Slows worsening of severe malignant osteopetrosis.
Usual adult dose
Chronic granulomatous disease: 50 mcg/m² under the skin three times weekly. Osteopetrosis: 50 mcg/m² under the skin three times weekly.
Usual dose in children
Chronic granulomatous disease: 50 mcg/m² under the skin three times weekly. Osteopetrosis: 1.5 mcg/kg under the skin three times weekly.
Common side effects
- Fever, chills, headache, fatigue, or muscle aches
- Injection-site pain, redness, or swelling
- Nausea, vomiting, or diarrhea
- Low white blood cell or platelet counts
Important warnings
- Can worsen bone marrow suppression; blood counts require monitoring.
- Use cautiously with heart or nervous system disorders.
- May cause severe allergic reactions.
- Dose adjustment may be needed with significant liver or kidney problems.
Pregnancy
Human pregnancy information is limited. Use only when potential benefits justify potential risks.
Breastfeeding
It is unknown whether interferon gamma-1b passes into breast milk; information on effects is limited.
Interactions
- Medicines that suppress bone marrow may increase blood-cell problems.
- Other medicines affecting the liver may increase liver-related risks.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.