About dronedarone hydrochloride
Antiarrhythmic medicine
Used for
- Helps maintain normal heart rhythm in adults with certain types of atrial fibrillation or flutter.
Usual adult dose
400 mg by mouth twice daily with meals.
Common side effects
- Diarrhoea, nausea, vomiting, or abdominal pain
- Slow heartbeat
- Rash or itching
- Raised liver enzymes
Important warnings
- Not suitable for permanent atrial fibrillation or severe heart failure.
- Can cause serious liver injury, lung problems, or abnormal heart rhythms.
- Avoid in severe liver or kidney problems.
- Seek urgent assessment for worsening breathlessness, swelling, or rapid weight gain.
Pregnancy
Not recommended during pregnancy; human safety information is limited.
Breastfeeding
Breastfeeding is not recommended during treatment because it is unknown whether the medicine enters breast milk.
Interactions
- Avoid strong CYP3A inhibitors, such as ketoconazole and clarithromycin.
- Can interact with warfarin and other blood thinners; monitoring may be needed.
- Avoid grapefruit juice, which can increase medicine levels.
- Can increase levels of digoxin and some statins.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.