About ketoprofen
Nonsteroidal anti-inflammatory drug (NSAID)
Used for
- Short-term treatment of moderate pain
- Pain and inflammation from musculoskeletal conditions
- Postoperative pain
Usual adult dose
Injection dosing varies by country and indication; commonly 100 mg by deep intramuscular injection once or twice daily, short term.
Common side effects
- Stomach pain, indigestion, nausea
- Injection-site pain or irritation
- Dizziness or headache
- Fluid retention or increased blood pressure
Important warnings
- May cause stomach ulcers, bleeding, or perforation.
- Can increase risks of heart attack and stroke, especially with higher doses or prolonged use.
- Avoid with active stomach bleeding, severe kidney disease, or aspirin-sensitive asthma.
- Do not combine with other NSAIDs unless directed by a clinician.
Pregnancy
Avoid from 20 weeks unless specifically prescribed; avoid from 30 weeks because of fetal heart and labor risks.
Breastfeeding
Generally avoid; seek an alternative because information on injectable ketoprofen is limited.
Interactions
- Anticoagulants and antiplatelet medicines increase bleeding risk.
- Other NSAIDs, including aspirin, increase stomach and kidney risks.
- ACE inhibitors, ARBs, and diuretics may worsen kidney function.
- Lithium or methotrexate levels may rise.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.