About hydrochlorothiazide
Thiazide diuretic
Used for
- High blood pressure
- Swelling caused by heart, kidney, or liver conditions
Usual adult dose
High blood pressure: usually 12.5–25 mg once daily. Swelling: commonly 25–100 mg daily, adjusted to response.
Usual dose in children
For swelling or high blood pressure: usually 1–2 mg/kg daily, adjusted by a clinician; maximum 100 mg daily.
Common side effects
- Frequent urination
- Dizziness or light-headedness
- Low potassium or sodium
- Increased uric acid or blood sugar
Important warnings
- May cause dehydration, low blood pressure, or electrolyte disturbances.
- Use cautiously with kidney or liver disease, gout, or diabetes.
- Seek urgent care for severe rash, breathing difficulty, or eye pain with vision changes.
Pregnancy
May affect blood volume and is generally avoided for routine high blood pressure in pregnancy; use only when a clinician considers it necessary.
Breastfeeding
Small amounts may enter milk; higher doses can reduce milk supply. Discuss use with a clinician.
Interactions
- Lithium: hydrochlorothiazide can raise lithium levels.
- Digoxin: low potassium may increase abnormal heart rhythm risk.
- NSAIDs such as ibuprofen may reduce its effect and affect kidney function.
- Other blood-pressure medicines may increase dizziness or low blood pressure.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.