About loratadine + phenylephrine hcl
Antihistamine and decongestant combination
Used for
- Relieves hay fever and allergy symptoms, including sneezing and runny nose.
- Temporarily relieves nasal congestion associated with colds or allergies.
Usual adult dose
For immediate-release products, adults commonly take loratadine 5 mg with phenylephrine 10 mg every 4 hours; follow the product label and maximum daily dose.
Usual dose in children
Children’s dosing depends on age and product labeling; combination products may not be suitable for young children.
Common side effects
- Headache
- Nervousness or restlessness
- Dizziness
- Dry mouth
Important warnings
- Phenylephrine may raise blood pressure or heart rate.
- Use caution with heart disease, high blood pressure, thyroid disease, or glaucoma.
- Do not combine with monoamine oxidase inhibitors or use within 14 days of stopping them.
- Check other medicines to avoid duplicate antihistamines or decongestants.
Pregnancy
Safety is not well established for this combination; phenylephrine is generally avoided unless a clinician recommends it.
Breastfeeding
Loratadine is generally considered compatible with breastfeeding; phenylephrine may reduce milk supply.
Interactions
- Monoamine oxidase inhibitors can cause dangerous blood pressure increases with phenylephrine.
- Other stimulants or decongestants may increase heart rate or blood pressure.
- Some medicines that affect liver enzymes may alter loratadine levels.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.