About dorzolamide hydrochloride + timolol maleate
Carbonic anhydrase inhibitor and beta blocker
Used for
- Lowers eye pressure in open-angle glaucoma
- Lowers eye pressure in ocular hypertension
Usual adult dose
One drop in the affected eye(s) twice daily.
Usual dose in children
Not routinely used in children; safety and dosing depend on age and specialist guidance.
Common side effects
- Eye burning, stinging, or irritation
- Bitter taste
- Blurred vision
- Slow heartbeat or breathing difficulty
Important warnings
- Avoid with asthma, severe chronic lung disease, or certain heart rhythm problems.
- Can be absorbed into the bloodstream and affect heart or lung function.
- Remove contact lenses before use; some formulations contain benzalkonium chloride.
- Other eye drops should generally be separated by at least 10 minutes.
Pregnancy
Use only when clearly needed; potential fetal effects require consideration by a healthcare professional.
Breastfeeding
May enter breast milk and affect an infant; use requires a careful benefit-risk assessment.
Interactions
- Oral beta blockers may increase slow heartbeat or low blood pressure.
- Some calcium-channel blockers and antiarrhythmics can increase heart effects.
- Other carbonic anhydrase inhibitors may increase adverse effects.
- Strong CYP2D6 inhibitors, such as fluoxetine, may increase beta-blocker effects.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.