About tetracosactide
Synthetic ACTH analogue
Used for
- Diagnostic testing of adrenal gland function
- Treatment of selected inflammatory or autoimmune conditions under specialist supervision
Usual adult dose
Diagnostic testing: commonly 0.25 mg by injection, with cortisol measured before and after. Depot treatment varies by condition and specialist protocol.
Usual dose in children
Diagnostic testing: commonly 0.25 mg by injection; depot treatment doses are specialist- and condition-specific.
Common side effects
- Injection-site reactions
- Fluid retention and increased blood pressure
- Raised blood sugar
- Mood changes or increased infection risk
Important warnings
- Depot treatment can suppress adrenal function; prolonged use may require gradual dose reduction.
- May worsen infections, diabetes, high blood pressure, or stomach ulcers.
- Avoid live vaccines during immunosuppressive treatment.
- Use only with clinical monitoring; diagnostic and depot formulations are not interchangeable.
Pregnancy
Use only when clearly needed; prolonged treatment may affect fetal growth and the newborn’s adrenal function.
Breastfeeding
Information is limited; use requires weighing maternal need against potential infant exposure.
Interactions
- May increase potassium loss with diuretics or amphotericin.
- Can alter blood-thinning effects of anticoagulants.
- May increase stomach bleeding risk with NSAIDs.
- Live vaccines may cause infection during immunosuppressive treatment.
AI-generated from general medical knowledge, not from this product's official leaflet. It may be incomplete or out of date. Not medical advice — ask a pharmacist or doctor before making any decision.